Searchable abstracts of presentations at key conferences in endocrinology

ea0056p668 | Neuroendocrinology | ECE2018

Cigarette smoking and neuroreceptors genetic variations: a handshake between genetic and environmental factors leading to nicotine addiction

Zafar Muhammad Mobeen , Ahmad Imtiaz , Raja Muhammad Saqlain , Kiani Shagufta , Ahmed Muhammad Sheeraz , Raza Shakeel , Gulfraz Muhammad , Kaukab Ghazala

Cigarette smoking is the major cause of disease related deaths in the world. Cigarette smoke contains many harmful chemicals, among them nicotine is the most potent one. The root cause of smoking hazards is nicotine addiction or dependence (ND). Environmental as well as genetic factors are reported to influence smoking which leads to nicotine addiction in all age groups especially. Neurexin1 is a cell adhesion protein important for synapse formation and CHRNB4 is chol...

ea0056p669 | Neuroendocrinology | ECE2018

Association of OPRD1 rs569356 SNP with Stress Response in opioid addicts

Rashid Faiqa , Zafar Muhammad Mobeen , Ahmed Imtiaz , Jabeen Shagusta , Ahmad Muhammad Sheeraz , Minhas Nasir Mehmood , Kaukab Ghazala

As a lingering, often deteriorating brain disease, addiction causes neurotic drug seeking and utilization along with injurious significances to the addicts and to those living around them. Biological, genetic and a number of intrinsic and extrinsic environmental constituents are most vital in entire risk factors of drug addiction. Among addictive drugs opioid dependence is considered as the most deliberated drug abuse disorder and a major social dilemma worldwide. Opioids indu...